Correlation between clinical characteristics and proliferative activity in patients with craniopharyngioma

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Correlation between clinical characteristics and proliferative activity in patients with craniopharyngioma.

OBJECTIVES The aim of the study was to correlate the Ki-67 and cyclin A labelling index (LI) with clinical characteristics and risk of recurrence of craniopharyngiomas. METHODS 47 consecutive patients were studied, 21 female and 26 male, aged 34.3 (2.8) years. Immunohistochemical analysis was performed on paraffin wax embedded material using monoclonal antibodies directed against the prolifer...

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Introduction: Proliferation of cancer cells and the potential of metastasis depend on the activity of different biomarkers such as proliferative ones. Proliferative biomarkers including ki-67, cyclin E1, cyclin D1, p27, and p21 were analyzed through immunohistochemistry (IHC) in previous studies. Methods: The current study aimed at investigating the utilizing role of RT-PCR in studying prolife...

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The Interaction Between the Expression of Proliferative Biomarkers and Clinical Characteristics in Breast Cancer

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ژورنال

عنوان ژورنال: Journal of Neurology, Neurosurgery & Psychiatry

سال: 2004

ISSN: 0022-3050

DOI: 10.1136/jnnp.2003.012781